Beta-RAM部分文章

Beta-RAM 部分应用文献列表

Molecular imaging of glycan chains couples cell-wall polysaccharide architecture to bacterial cell morphology

Nature Communications volume 9, Article number: 1263 (2018)

2′-O-methylation in mRNA disrupts tRNA decoding during translation elongation

Nature Structural & Molecular Biology volume 25, pages208–216 (2018) 

Loss of an Androgen-Inactivating and Isoform-Specific HSD17B4 Splice Form Enables Emergence of Castration-Resistant Prostate Cancer

Cell Reports,Volume 22, Issue 3, p809–819, 16 January 2018

Functional silencing of HSD17B2 in prostate cancer promotes disease progression

CLINICAL CANCER RESEARCH September 18, 2018

Direct metabolic interrogation of dihydrotestosterone biosynthesis from adrenal precursors in primary prostatectomy tissues

CLINICAL CANCER RESEARCH  July 21, 2017 

Redirecting abiraterone metabolism to fine-tune prostate cancer anti-androgen therapy

Nature volume533, pages547–551 (26 May 2016)

N6-methyladenosine in mRNA disrupts tRNA selection and translation-elongation dynamics

Nature Structural & Molecular Biology 23, 110–115,2016

Accuracy of genetic code translation and its orthogonal corruption by aminoglycosides and Mg2+ions 

Nucleic Acids Research, Volume 46, Issue 3, 16 February 2018, Pages 1362–1374

Molecular mechanism of viomycin inhibition of peptide elongation in bacteria

PNAS January 26, 2016 113 (4) 978-983

Stabilin-1 and Stabilin-2 are specific receptors for the cellular internalization of phosphorothioate-modified antisense oligonucleotides (ASOs) in the liver

Nucleic Acids Research, Volume 44, Issue 6, 7 April 2016, Pages 2782–2794

Spatially Organized Enzymes DriveCofactor-Coupled Cascade Reactions

J. Am. Chem. Soc., 2016, 138 (9), pp 3012–3021

Ribosomal Peptide Syntheses from Activated Substrates Reveal Rate Limitation by an Unexpected Step at the Peptidyl Site

J Am Chem Soc. 2016 Dec 7;138(48):15587-15595

Conversion of abiraterone to D4A drives anti-tumour activity in prostate cancer

Nature volume523, pages347–351 (16 July 2015)

Making water-soluble integral membrane proteins in vivo using an amphipathic protein fusion strategy

Nature Communications volume6, Article number: 6826 (2015)

Structural Insights into Assembly and Regulation of the Plasma Membrane Phosphatidylinositol 4-Kinase Complex

Developmental cell,Volume 28, Issue 1, 13 January 2014

Targeted delivery of antisense oligonucleotides to hepatocytes using triantennary N-acetyl galactosamine improves potency 10-fold in mice

Nucleic Acids Research, Volume 42, Issue 13, 29 July 2014, Pages 8796–8807

A Gain-of-Function Mutation in DHT Synthesis in Castration-Resistant Prostate Cancer

Cell ,Volume 154, Issue 5, 29 August 2013, Pages 1074-1084

Measurement of phosphoinositides in the zebrafish Danio rerio

Nature Protocols volume8, pages1058–1072 (2013)

Development of orally active inhibitors of protein and cellular fucosylation

PNAS April 2, 2013. 110 (14) 5404-5409

Mycobacterium tuberculosis is extraordinarily sensitive to killing by a vitamin C-induced Fenton reactio

Nature Communications volume4, Article number: 1881 (2013)

Genetic code translation displays a linear trade-off between efficiency and accuracy of tRNA selection

Proc Natl Acad SciUSA January 3, 2012 109 (1) 131-136

Structural insights into the stereochemistry of the cyclooxygenase reaction

Nature 405, 97–101,2000

Pyrazinamide inhibits the eukaryotic-like fatty acid synthetase I (FASI) of Mycobacterium tuberculosis

Nature Medicine 6, 1043–1047,2000